Estructura,replicacion y reparacion del adn bioquimica. Scribd is the worlds largest social reading and publishing site. New patterns of inheritance in mitochondrial disease pdf. Oct 05, 2016 replicacion del adn con audio latino duration. Drp1is involved in the fission of the mitochondrial outer membrane, perhaps directly or perhaps through its ability to recruit additional fission machinery components. Le grenier genealogique genetique adn mitochondrial. Dna mitocondrial y enfermedades y rasgos hereditarios harrison. Nucleoids contain between 3 and 4 mitochondrial genomes and as many as 20 different polypeptides miyakawa et al.
Mitochondrial dna structure and function complexes, which are spherical or ovoid, measuring 0. Eukaryotic mitochondrial organelles contain a genome separate and dis tinct from that of the nucleus. Adn mitocondrial y enfermedades relacionadas chemevol uah. Modelo conservativo modelo dispersivo modelo semiconservativo. Strategies designed to define both cisacting elements and transacting factors re quired for mtdna replication have been developed over the last 25 years.
Mitochondrial dna replication in most cases, mtdna replication in mammals is an asynchronous pro cess, beginning at the origin of the hstrand replication oh and proceed ing around two thirds of the mitochondrial genome, until the origin of the. Adn polimerasas procariotas polimerasas procesividad 3200 1. Dna mitochondrial metabolism, twinkle is involved in mitochondrial. Mutaciones las mutaciones tambien pueden ocurrir por fenomenos post replicacion mutagenos fisicos, quimicos, etc. Although limited in genetic content, ex pression of mitochondrial dna mtdna is an essential function in most eukaryotes, and therefore the genome is not dispensable.
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